Fillion Synthetic
Organic/Organometallic Research Group
University of Waterloo, Waterloo, Ontario, Canada
Publications
2011
N-Fused Indolines through Non-Carbonyl
Stabilized Rhodium Carbenoid C-H Insertion of N-Aziridinyl
Imines
Stuart Mahoney and Eric Fillion
Chem. Eur. J. Accepted
Catalytic
Intramolecular Friedel-Crafts
Reaction of Benzyl Meldrum’s Acid Derivatives: Preparation of 5,6-Dimethoxy-2-Methyl-1-Indanone
Tiantong Lou, E-Ting
Liao, Ashraf Wilsily and Eric Fillion
2010
Meldrum’s
Acids and 5-Alkylidene Meldrum’s Acids in Catalytic Carbon-Carbon Bond-Forming
Processes
Aaron M. Dumas and Eric Fillion
Acc.
Chem. Res. 2010, 43, 440-454
2009
Asymmetric
Addition of Alkenylstannanes to Alkylidene
Meldrum’s Acids
Stuart J. Mahoney, Aaron M. Dumas
and Eric Fillion
Org.
Lett. 2009,
11, 5346-5349
Asymmetric
Synthesis of All-Carbon Benzylic Quaternary Stereocenters via Conjugate Addition to Alkylidene
and Indenylidene Meldrum’s Acids
Ashraf Wilsily
and Eric Fillion
J.
Org. Chem. 2009, 74, 8583-8594
Hydrogenolysis of Unstrained Carbon-Carbon sigma-Bonds-Stereoselective
Entry Into Benzylic Tertiary
Centers
Ashraf Wilsily,
Yen Nguyen, and Eric Fillion
J.
Am. Chem. Soc. 2009, 131,
15606-15607
Enantioselective Rhodium-Catalyzed Conjugate Alkynylation of
5-Benzylidene Meldrum’s Acids with TMS-acetylene
Eric Fillion
and Alexander K. Zorzitto
J. Am. Chem. Soc. 2009, 131,
14608-14609
Functionalization
of Csp3-H Bond- Sc(OTf)3-Catalyzed
Domino 1,5-Hydride Shift/Cyclization/Friedel-Crafts Acylation
Reaction of Benzylidene Meldrum’s Acids
Stuart J. Mahoney, David T. Moon,
Jon Hollinger, and Eric Fillion
Tetrahedron Letters 2009, 50, 4706-4709
Scandium
Triflate-Catalyzed Intramolecular
Friedel-Crafts Acylation with Meldrum’s Acids:
Insight into the Mechanism
Eric Fillion
and Dan Fishlock
Tetrahedron 2009, 65, 6682-6695 (invited contribution
to special issue in honour of Prof. Larry Overman)
Enantioselective Copper-Catalyzed Conjugate Addition of Dimethylzinc
to 5-(1-Arylalkylidene) Meldrum’s Acids
Ashraf Wilsily,
Tiantong Lou and Eric Fillion
Synthesis
2009,
2066-2072 (invited contribution to special issue on phosphoramidite ligands)
Palladium-Catalyzed
Intramolecular Reactions of (E)-2,2-Disubstituted 1-Alkenyldimethylalanes with Aryl Triflates
Eric Fillion,
Vincent É. Trépanier, Jarkko
J. Heikkinen, Anna A. Remorova,
Rebeka J. Carson, Julie M. Goll
and Adam Seed
Organometallics 2009, 28,
3518-3531
Sc(OTf)3-Catalyzed Conjugate Allylation
of Alkylidene Meldrum’s Acids
Aaron M. Dumas and Eric Fillion
Org. Lett.
2009,
11, 1919-1922
Probing
Persistent Intramolecular C-H···X (X = O, S, Br, Cl, and F) Bonding in Solution Using Benzyl Meldrum’s Acid
Derivatives
Eric Fillion,
Ashraf Wilsily and Dan Fishlock
J. Org. Chem. 2009, 74, 1259-1267
2008
Tuning
the Reactivity of Palladium Carbenes Derived from Diphenylketene
Julie M. Goll
and Eric Fillion
Organometallics,
2008,
27, 3622-3625
Asymmetric
Synthesis of Carboxylic Acid Derivatives Having an All-Carbon α-Quaternary
Center through Cu-Catalyzed 1,4-Addition of Dialkylzinc
Reagents to 2-Aryl Acetate Derivatives
Ashraf Wilsily
and Eric Fillion
Org.
Lett. 2008, 10, 2801-2804
Synthesis of Fused 4,5-Disubstituted
Indole Ring Systems by Intramolecular
Friedel-Crafts Acylation of 4-Substituted Indoles
Eric Fillion
and Aaron M. Dumas
J.
Org. Chem. 2008, 73,
2920-2923
Sequential Rh(I)/Pd-Catalyzed 1,4-Addition/Intramolecular
Allylation: Stereocontrolled
Construction of gamma-Butyrolactones and Cyclopropanes
Eric Fillion,
Sébastien Carret, Lauren G.
Mercier, and Vincent É. Trepanier
2007
Ambiphilic Vinylcarbenoid Reactivity of (α-(Tributylstannyl)-π-allyl)palladium(II) Species
Vincent É. Trepanier
and Eric Fillion
Organometallics 2007, 26, 30-32
A General and Practical Preparation of Alkylidene Meldrum’s Acids
Aaron M. Dumas, Adam Seed,
Alexander K. Zorzitto, and Eric Fillion
Tetrahedron Lett.
2007, 48, 7072-7074
2006
Asymmetric
Cu-Catalyzed 1,6-Conjugate Addition of Dialkylzinc Reagents to 5-(3-Aryl-2-propenylidene)
Meldrum’s Acids
Eric Fillion,
Ashraf Wilsily, and E-Ting Liao
Tetrahedron: Asymmetry 2006, 17,
2957-2959
Modular Synthesis of Tetrahydrofluorenones from 5-Alkylidene Meldrum’s Acids
Eric Fillion,
Aaron M. Dumas, and Sylvia A. Hogg
J. Org. Chem. 2006, 71, 9899-9902
Asymmetric
Synthesis of All-Carbon Benzylic Quaternary Stereocenters via Cu-Catalyzed Conjugate Addition of Dialkylzinc Reagents to 5-(1-Arylalkylidene) Meldrum's
Acids
Eric Fillion
and Ashraf Wilsily
J. Am. Chem.
Soc. 2006, 128, 2774-2775
Yb(OTf)3-Catalyzed Reactions of
5-Alkylidene Meldrum's Acids with Phenols - One-Pot Assembly of
3,4-Dihydrocoumarins, 4-Chromanones, Coumarins, and Chromones
Eric Fillion, Aaron M. Dumas, Bryan A. Kuropatwa, Neil R. Malhotra, and Tamsyn C. Sitler.
J. Org. Chem. 2006, 71, 409-412
2005
Total Synthesis of (±)-Taiwaniaquinol
B via a Domino Intramolecular Friedel-Crafts
Acylation/Carbonyl a-tert-Alkylation Reaction
Eric Fillion and Dan Fishlock
J. Am. Chem Soc. 2005, 127, 13144-13145
Meldrum's Acids as Acylating Agents in the Catalytic Intramolecular
Friedel-Crafts Reaction
Eric Fillion,
Dan Fishlock, Ashraf Wilsily,
and Julie M. Goll
Oxidative coupling of 2-substituted 1,2-dihydro-1-naphthols
using Jones reagent: a simple entry into 3,3′-disubstituted 1,1′-binaphthyl-4,4′-diols
Eric Fillion, Vincent
E. Trépanier, Lauren G. Mercier, Anna A. Remorova and Rebekah J. Carson
Tetrahedron
Lett. 2005, 46, 1091-1094
2004
Palladium-Catalyzed Carbon-Carbon Bond Forming 1,2-Ligand Migration of Organoalanes
Eric Fillion, Rebekah J.
Carson, Vincent E. Trépanier, and Julie M. Goll
J. Am. Chem. Soc. 2004, 126,
15354-15355
2003
Cine Substitution in the Stille Coupling:
Evidence for the Carbenoid Reactivity of
sp3-gem-Organodimetallic Iodopalladio-trialkylstannylalkane
Intermediates
Eric Fillion and Nicholas J.
Taylor
J. Am. Chem. Soc. 2003, 125,
12700-12701
Efficient and Expedient Two-Step Pyranose-Retaining
Fluorescein-Conjugation of Complex Reducing Oligosaccharides: Galectin Oligosaccharide Specificity Studies in a
Fluorescence Polarization Assay
Christopher T. Öberg,
Susanne Carlsson, Eric Fillion,
Hakon Leffler, and Ulf J.
Nilsson
Bioconjugate
Chem. 2003, 14, 1289-1297
Convenient Access to Polysubstituted
1-Indanones by Sc(OTf)3-Catalyzed Intramolecular Friedel-Crafts
Acylation of Benzyl Medrum's Acid Derivatives
Eric Fillion and Dan Fishlock
Enantioselective Synthesis of Bicyclo[6.1.0]nonane-9-Carboxylic
Acids via Me2AlOTf-Promoted Intramolecular
Friedel-Crafts Alkylation of Arenes
with the g-Lactone Moiety of 3-Oxa-Bicyclo[3.1.0]hexan-2-Ones
Eric Fillion and Rachel L. Beingessner
J. Org. Chem. 2003, 68, 9485-9488
